Отправить статью по E-mail Antibacterial activity of [1Fe-2S]- and [2Fe-2S]-nitrosyl complexes as nitric oxide donors
- Авторы: Mumyatova V.A.1,2, Kozub G.I.1,2, Kondrat’eva T.A.1,2, Terent’ev A.A.1,2,3, Sanina N.A.1,2,3
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Учреждения:
- Institute of Problems of Chemical Physics, Russian Academy of Sciences
- Medicinal Chemistry Research and Education Center, Moscow Region State University
- Department of Fundamental Physical and Chemical Engineering, M. V. Lomonosov Moscow State University
- Выпуск: Том 68, № 5 (2019)
- Страницы: 1025-1030
- Раздел: Full Article
- URL: https://journal-vniispk.ru/1066-5285/article/view/243375
- DOI: https://doi.org/10.1007/s11172-019-2514-3
- ID: 243375
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Аннотация
The biological activity of a series of sulfur-nitrosyl iron complexes (NICs) depends on the structure of the ligands and the position of the functional groups in the aromatic ring of the ligand. Differences in susceptibility of the gram-positive and gram-negative bacteria to the NICs was found. The series of the studied NICs suppresses the formation of biofilms of Micrococcus luteus bacteria. The obtained results demonstrate that the studied complexes can serve as the basis for the preparation of antibacterial agents.
Об авторах
V. Mumyatova
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Medicinal Chemistry Research and Education Center, Moscow Region State University
Email: sanina@icp.ac.ru
Россия, 1 prosp. Akad. Semenova, Chernogolovka, Moscow Region, 142432; 24 ul. Very Voloshinoi, Mytishchi, Moscow Region, 141014
G. Kozub
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Medicinal Chemistry Research and Education Center, Moscow Region State University
Email: sanina@icp.ac.ru
Россия, 1 prosp. Akad. Semenova, Chernogolovka, Moscow Region, 142432; 24 ul. Very Voloshinoi, Mytishchi, Moscow Region, 141014
T. Kondrat’eva
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Medicinal Chemistry Research and Education Center, Moscow Region State University
Email: sanina@icp.ac.ru
Россия, 1 prosp. Akad. Semenova, Chernogolovka, Moscow Region, 142432; 24 ul. Very Voloshinoi, Mytishchi, Moscow Region, 141014
A. Terent’ev
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Medicinal Chemistry Research and Education Center, Moscow Region State University; Department of Fundamental Physical and Chemical Engineering, M. V. Lomonosov Moscow State University
Email: sanina@icp.ac.ru
Россия, 1 prosp. Akad. Semenova, Chernogolovka, Moscow Region, 142432; 24 ul. Very Voloshinoi, Mytishchi, Moscow Region, 141014; 1 Leninskie Gory, Moscow, 119991
N. Sanina
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Medicinal Chemistry Research and Education Center, Moscow Region State University; Department of Fundamental Physical and Chemical Engineering, M. V. Lomonosov Moscow State University
Автор, ответственный за переписку.
Email: sanina@icp.ac.ru
Россия, 1 prosp. Akad. Semenova, Chernogolovka, Moscow Region, 142432; 24 ul. Very Voloshinoi, Mytishchi, Moscow Region, 141014; 1 Leninskie Gory, Moscow, 119991
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