电邮这篇文章 Kinetic resolution of racemic 3-tert-butyl-3,4-dihydro-2H-[1,4]benzoxazine via acylation with chiral acyl chlorides
- 作者: Vakarov S.A.1, Gruzdev D.A.1,2, Chulakov E.N.1, Levit G.L.1,2, Krasnov V.P.1
-
隶属关系:
- I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
- Ural Federal University named after the first President of Russia B. N. Yeltsin
- 期: 卷 68, 编号 4 (2019)
- 页面: 841-847
- 栏目: Full Article
- URL: https://journal-vniispk.ru/1066-5285/article/view/243355
- DOI: https://doi.org/10.1007/s11172-019-2494-3
- ID: 243355
如何引用文章
开放存取
##reader.subscriptionAccessGranted##
订阅存取
详细
A comparative study of the kinetic resolution of racemic 3-tert-butyl-3,4-dihydro-2H-[1,4]-benzoxazine through the acylation by various chiral acyl chlorides was carried out. A preparative method for obtaining enantiomerically pure (S)-3-tert-butyl-3,4-dihydro-2H-[1,4]benzoxazine can be based on the acylation with N-phthaloyl-(S)-phenylalanyl or (R)-2-phenoxypropionyl chlorides, followed by the acid hydrolysis of the corresponding diastereomerically pure amides.
作者简介
S. Vakarov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
编辑信件的主要联系方式.
Email: savakarov@ios.uran.ru
俄罗斯联邦, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
D. Gruzdev
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: savakarov@ios.uran.ru
俄罗斯联邦, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990; 19 ul. Mira, Ekaterinburg, 620002
E. Chulakov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: savakarov@ios.uran.ru
俄罗斯联邦, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
G. Levit
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: savakarov@ios.uran.ru
俄罗斯联邦, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990; 19 ul. Mira, Ekaterinburg, 620002
V. Krasnov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: savakarov@ios.uran.ru
俄罗斯联邦, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620990
补充文件
