Synthesis of succinic monoamide avermectin esters

M. A. Shchetinina; E. I. Chernoburova; N. G. Kolotyrkina; M. Kh. Dzhafarov; F. I. Vasilevich; I. V. Zavarzin

doi:10.1007/s11172-019-2528-x

Synthesis of succinic monoamide avermectin esters

作者: Shchetinina M.A.¹, Chernoburova E.I.¹, Kolotyrkina N.G.¹, Dzhafarov M.K.², Vasilevich F.I.², Zavarzin I.V.¹
隶属关系:
1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
2. K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology
期: 卷 68, 编号 5 (2019)
页面: 1116-1121
栏目: Full Article
URL: https://journal-vniispk.ru/1066-5285/article/view/243389
DOI: https://doi.org/10.1007/s11172-019-2528-x
ID: 243389

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详细

Reaction of avermectin B₁ hemisuccinate with N-hydroxysuccinimide and N,N’-dicyclohexylcarbodiimide followed by amination provided succinic monoamide avermectine esters that are potential antiparasitics.