Email this article Mass Spectrometry Profiling of the Protein Composition of Blood Plasma of Colorectal Cancer Patients
- Authors: Kaysheva A.L.1, Kopylov A.T.1, Pleshakova T.O.1, Kushlinskii N.E.2, Nikitaev V.G.3, Druzhinina E.A.3, Archakov A.I.1, Ivanov Y.D.1
-
Affiliations:
- Institute of Biomedical Chemistry
- N. N. Blokhin National Medical Research Centre of Oncology
- National Research Nuclear University “MEPhI”
- Issue: Vol 45, No 9 (2018)
- Pages: 279-281
- Section: Article
- URL: https://journal-vniispk.ru/1068-3356/article/view/228722
- DOI: https://doi.org/10.3103/S1068335618090051
- ID: 228722
Cite item
Open Access
Access granted
Subscription Access
Abstract
The objective of the study is themass spectrometry analysis of the protein composition in blood plasma samples of large intestine cancer patients. Protein profiles of 58 blood plasma samples of large intestine cancer patients and healthy volunteers are analyzed using ultrahigh-resolution panoramic mass spectrometry. It is shown that the coincidence of identifications in the protein composition samples of intestine cancer patients and healthy men is 60–80%. Samples of intestines cancer patients contain proteins involved in the interaction with ribonucleic acid, proteins, and lowmolecular substrata.
About the authors
A. L. Kaysheva
Institute of Biomedical Chemistry
Author for correspondence.
Email: kaysheva1@gmail.com
Russian Federation, Pogodinskaya ul. 10/8, Moscow, 119121
A. T. Kopylov
Institute of Biomedical Chemistry
Email: kaysheva1@gmail.com
Russian Federation, Pogodinskaya ul. 10/8, Moscow, 119121
T. O. Pleshakova
Institute of Biomedical Chemistry
Email: kaysheva1@gmail.com
Russian Federation, Pogodinskaya ul. 10/8, Moscow, 119121
N. E. Kushlinskii
N. N. Blokhin National Medical Research Centre of Oncology
Email: kaysheva1@gmail.com
Russian Federation, Kashirskoe sh. 23, Moscow, 115478
V. G. Nikitaev
National Research Nuclear University “MEPhI”
Email: kaysheva1@gmail.com
Russian Federation, Kashirskoe sh. 31, Moscow, 115409
E. A. Druzhinina
National Research Nuclear University “MEPhI”
Email: kaysheva1@gmail.com
Russian Federation, Kashirskoe sh. 31, Moscow, 115409
A. I. Archakov
Institute of Biomedical Chemistry
Email: kaysheva1@gmail.com
Russian Federation, Pogodinskaya ul. 10/8, Moscow, 119121
Yu. D. Ivanov
Institute of Biomedical Chemistry
Email: kaysheva1@gmail.com
Russian Federation, Pogodinskaya ul. 10/8, Moscow, 119121
Supplementary files
