Synthesis of 6-methyl-2-[2-phenyl-2-(arylhydrazono)ethyl]-3 Н -pyrimidine-4-ones and their oxidation by hydrogen peroxide and selenium dioxide

A. A. Yavolovskii; S. M. Pluzhnik-Gladyr; Yu. E. Ivanov; D. E. Stepanov; L. V. Grishchuk; G. L. Kamalov

doi:10.1134/S1070363216070112

Synthesis of 6-methyl-2-[2-phenyl-2-(arylhydrazono)ethyl]-3Н-pyrimidine-4-ones and their oxidation by hydrogen peroxide and selenium dioxide

Authors: Yavolovskii A.A.¹, Pluzhnik-Gladyr S.M.¹, Ivanov Y.E.¹, Stepanov D.E.¹, Grishchuk L.V.¹, Kamalov G.L.¹
Affiliations:
1. Bogatskii Physicochemical Institute
Issue: Vol 86, No 7 (2016)
Pages: 1604-1607
Section: Article
URL: https://journal-vniispk.ru/1070-3632/article/view/215653
DOI: https://doi.org/10.1134/S1070363216070112
ID: 215653

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Abstract

The reaction of 6-methyl-2-(2-oxo-2-phenylethylidene)-2,3-dihydropyrimidine-4(1H)-one with arylhydrazines leads in high yields to the corresponding hydrazones, in which the ethylidene fragment of the starting compound is transformed to the ethylene fragment. By oxidation of the hydrazones with hydrogen peroxide or selenium dioxide the corresponding 6-methyl-2-[2-phenyl-2-(arylhydrazono)acetyl]-3H-pyrimidine-4-ones were synthesized.