One-pot synthesis of 2-amino-4H-chromenes catalyzed by Fe(ClO4)3/SiO2


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Abstract

A highly efficient one-pot three-component synthesis of 2-amino-3-cyano-4H-chromenes has been developed by annulation of aldehydes, malononitrile and dimedone in the presence of Fe(ClO4)3/SiO2 as a catalyst in acetonitrile under reflux conditions. The simple experimental procedure, short reaction times and high yields are the advantages of this method. A probable mechanism of the process is proposed.

About the authors

F. K. Behbahani

Department of Chemistry, Karaj Branch

Author for correspondence.
Email: Farahnazkargar@yahoo.com
Iran, Islamic Republic of, Karaj

M. Naderi

Department of Chemistry, Karaj Branch

Email: Farahnazkargar@yahoo.com
Iran, Islamic Republic of, Karaj

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