Email this article Synthesis of 9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2Н,5Н)-diones
- Authors: Nasakin O.E.1, Kazantseva M.I.1, Gein V.L.2
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Affiliations:
- Chuvash State University
- Perm State Pharmaceutical Academy
- Issue: Vol 87, No 1 (2017)
- Pages: 154-155
- Section: Letters to the Editor
- URL: https://journal-vniispk.ru/1070-3632/article/view/218084
- DOI: https://doi.org/10.1134/S107036321701025X
- ID: 218084
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Abstract
The reaction in a mixture of 1,3-cyclohexanedione (dimedone), arylaldehyde, and ammonium acetate at 160°C during 10–15 min in the absence of solvent leads to the formation of 9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-diones. The structure of the products has been confirmed by IR and 1H NMR spectroscopy data. Antimicrobial activity of the obtained compounds has been studied.
About the authors
O. E. Nasakin
Chuvash State University
Email: geinvl48@mail.ru
Russian Federation, Cheboksary
M. I. Kazantseva
Chuvash State University
Email: geinvl48@mail.ru
Russian Federation, Cheboksary
V. L. Gein
Perm State Pharmaceutical Academy
Author for correspondence.
Email: geinvl48@mail.ru
Russian Federation, ul. Polevaya 2, Perm, 614000
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