Synthesis and antimicrobial activity of novel 5-[(1H-indol-3-yl)methylene]thiazolidine-2,4-dione–[1,2,3]triazole hybrids
- Authors: Kamala L.1, Veena B.S.2, Anantha Lakshmi P.V.1, Vasantha P.1, Sujatha E.2
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Affiliations:
- Department of Chemistry, University College for Women
- Department of Botany, University College of Science
- Issue: Vol 87, No 2 (2017)
- Pages: 316-321
- Section: Article
- URL: https://journal-vniispk.ru/1070-3632/article/view/218480
- DOI: https://doi.org/10.1134/S107036321702027X
- ID: 218480
Cite item
Abstract
5-[(1H-Indol-3-yl)methylene]thiazolidine-2,4-dione–[1,2,3]triazole hybrid derivatives were synthesized by click chemistry reaction and screened for antimicrobial activity against Gram positive and Gram negative bacteria and fungal species. All synthesized compounds were characterized by 1H and 13C NMR, IR and MS spectra. Antibacterial study indicated that several products demonstrated high activity and some products were determined to be potentially antifungal active agents.
Keywords
About the authors
L. Kamala
Department of Chemistry, University College for Women
Email: pvanantha.ou@gmail.com
India, Hyderabad, Telangana, 500007
B. S. Veena
Department of Botany, University College of Science
Email: pvanantha.ou@gmail.com
India, Hyderabad, Telangana, 500007
P. V. Anantha Lakshmi
Department of Chemistry, University College for Women
Author for correspondence.
Email: pvanantha.ou@gmail.com
India, Hyderabad, Telangana, 500007
P. Vasantha
Department of Chemistry, University College for Women
Email: pvanantha.ou@gmail.com
India, Hyderabad, Telangana, 500007
E. Sujatha
Department of Botany, University College of Science
Email: pvanantha.ou@gmail.com
India, Hyderabad, Telangana, 500007
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