Email this article Methyl Trifluoropyruvate in Cyclocondensation Reactions with N-Substituted Ureas
- Authors: Sokolov V.B.1, Aksinenko A.Y.1
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Affiliations:
- Institute of Physiologically Active Compounds of the Russian Academy of Sciences
- Issue: Vol 89, No 1 (2019)
- Pages: 153-156
- Section: Letters to the Editor
- URL: https://journal-vniispk.ru/1070-3632/article/view/222727
- DOI: https://doi.org/10.1134/S1070363219010286
- ID: 222727
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Abstract
The transformations of methyl trifluoropyruvate in cyclocondensation reactions with N-substituted ureas, leading to 3-substituted 5-hydroxy- or 5-methoxy-5-trifluoromethylimidazolidine-2,4-diones, were studied. The possibility of using 5-hydroxy-3-(prop-2-in-1-yl)-5-trifluoromethylimidazolidine-2,4-dione for modifying phenothiazine with a copper-catalyzed alkyne-azide 1,3-dipolar cycloaddition was shown.
About the authors
V. B. Sokolov
Institute of Physiologically Active Compounds of the Russian Academy of Sciences
Email: alaks@ipac.ac.ru
Russian Federation, Severnyi proezd 1, Chernogolovka, 142432
A. Yu. Aksinenko
Institute of Physiologically Active Compounds of the Russian Academy of Sciences
Author for correspondence.
Email: alaks@ipac.ac.ru
Russian Federation, Severnyi proezd 1, Chernogolovka, 142432
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