Synthesis of new nucleoside analogs containing amino bisphosphonic groups
- Authors: Vagapova L.I.1,2, Smolobochkin A.V.1, Gazizov A.S.1, Burilov A.R.1,2, Bogdanov A.A.2, Pudovik M.A.1, Sinyashin O.G.1
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Affiliations:
- Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
- Faculty of Chemistry
- Issue: Vol 52, No 9 (2016)
- Pages: 1335-1338
- Section: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/214965
- DOI: https://doi.org/10.1134/S1070428016090141
- ID: 214965
Cite item
Abstract
Adenosine derivatives containing a 2,2-bis(diethoxyphosphoryl)ethyl or 2,2-diphosphonoethyl group on the amino nitrogen atom were synthesized for the first time by reaction of 5′-chloro-5′-deoxy- and 5′-hydroxy-2′,3′-isopropylideneadenosine with tetraethyl ethene-1,1-diylbis(phosphonate) or tetrakis(trimethylsilyl) ethene-1,1-diylbis(phosphonate).
About the authors
L. I. Vagapova
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center; Faculty of Chemistry
Author for correspondence.
Email: vagapoval@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088; Leninskie gory 1, Moscow, 119991
A. V. Smolobochkin
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: vagapoval@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
A. S. Gazizov
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: vagapoval@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
A. R. Burilov
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center; Faculty of Chemistry
Email: vagapoval@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088; Leninskie gory 1, Moscow, 119991
A. A. Bogdanov
Faculty of Chemistry
Email: vagapoval@iopc.ru
Russian Federation, Leninskie gory 1, Moscow, 119991
M. A. Pudovik
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: vagapoval@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
O. G. Sinyashin
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: vagapoval@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
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