Отправить статью по E-mail Synthesis and antimicrobial activity of tryptanthrin adducts with ketones
- Авторы: Deryabin P.I.1, Moskovkina T.V.1, Shevchenko L.S.2, Kalinovskii A.I.2
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Учреждения:
- Far Eastern Federal University
- Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch
- Выпуск: Том 53, № 3 (2017)
- Страницы: 418-422
- Раздел: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/215946
- DOI: https://doi.org/10.1134/S1070428017030174
- ID: 215946
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Аннотация
Reactions of tryptanthrin with acetone, cyclopentanone, hexan-2-one, 4-methylpentan-2-one, 4-hydroxy-4-methylpentan-2-one, cyclohexanone, and butan-2-one in the presence of potassium carbonate afforded racemic phaitanthrin A and other addition products to the ketone group of tryptanthrin with high yields. Thermal dissociation, some chemical transformations, and antimicrobial activity of some adducts were studied, and inhibitory effect against gram-positive bacteria was found for particular derivatives.
Об авторах
P. Deryabin
Far Eastern Federal University
Email: moskovkinataisiya@mail.ru
Россия, ul. Sukhanova 8, Vladivostok, 690091
T. Moskovkina
Far Eastern Federal University
Автор, ответственный за переписку.
Email: moskovkinataisiya@mail.ru
Россия, ul. Sukhanova 8, Vladivostok, 690091
L. Shevchenko
Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch
Email: moskovkinataisiya@mail.ru
Россия, pr. 100 let Vladivostoku 159, Vladivostok, 690022
A. Kalinovskii
Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch
Email: moskovkinataisiya@mail.ru
Россия, pr. 100 let Vladivostoku 159, Vladivostok, 690022
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