Email this article Azido–tetrazole tautomerism of pyrano[3,4-c]pyridine derivatives
- Authors: Paronikyan E.G.1, Dashyan S.S.1, Minasyan N.S.2, Stepanyan G.M.1
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Affiliations:
- Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
- Molecular Structure Research Center, Scientific Technological Center of Organic and Pharmaceutical Chemistry
- Issue: Vol 53, No 6 (2017)
- Pages: 941-945
- Section: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/216449
- DOI: https://doi.org/10.1134/S1070428017060215
- ID: 216449
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Abstract
Treatment of N-aryl-8-hydrazinylpyrano[3,4-c]pyridine-5-carbonitriles with sodium nitrite in acetic acid afforded the corresponding 8-azido derivatives existing in solution as equilibrium mixtures with cyclic tetrazole tautomer whose fraction attains 48%. Lower solvent polarity and elevated temperature favor increased fraction of the azido tautomer.
About the authors
E. G. Paronikyan
Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: Shdashyan@gmail.com
Armenia, pr. Azatutyan 26, Yerevan, 0014
Sh. Sh. Dashyan
Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
Author for correspondence.
Email: Shdashyan@gmail.com
Armenia, pr. Azatutyan 26, Yerevan, 0014
N. S. Minasyan
Molecular Structure Research Center, Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: Shdashyan@gmail.com
Armenia, pr. Azatutyan 26, Yerevan, 0014
G. M. Stepanyan
Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
Email: Shdashyan@gmail.com
Armenia, pr. Azatutyan 26, Yerevan, 0014
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