Alkylation of 2-(hydroxyimino)-5H-[1,3]thiazolo[3,2-a]-pyrimidin-3(2H)-ones
- Authors: Lashmanova E.A.1, Larina V.S.1, Shiryaev A.K.1
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Affiliations:
- Samara State Technical University
- Issue: Vol 53, No 8 (2017)
- Pages: 1249-1252
- Section: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/216742
- DOI: https://doi.org/10.1134/S1070428017080152
- ID: 216742
Cite item
Abstract
Alkylation products were obtained from ethyl 2-(hydroxyimino)-7-methyl-3-oxo-5-aryl-2,3- dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidin-6-carboxylates at the treatment with alkyl halides, dimethyl sulfate, and diazomethane. Diazomethane alkylated the initial substrate at the oxygen atom of the carbonyl group of the thiazolidine fragment, the other reagents, at the oxygen atom of the hydroxyimino group.
About the authors
E. A. Lashmanova
Samara State Technical University
Author for correspondence.
Email: lashmanovaea@gmail.com
Russian Federation, Molodogvardeiskaya ul. 244, Samara, 443100
V. S. Larina
Samara State Technical University
Email: lashmanovaea@gmail.com
Russian Federation, Molodogvardeiskaya ul. 244, Samara, 443100
A. K. Shiryaev
Samara State Technical University
Email: lashmanovaea@gmail.com
Russian Federation, Molodogvardeiskaya ul. 244, Samara, 443100
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