Alkylation of 2-(hydroxyimino)-5H-[1,3]thiazolo[3,2-a]-pyrimidin-3(2H)-ones


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Abstract

Alkylation products were obtained from ethyl 2-(hydroxyimino)-7-methyl-3-oxo-5-aryl-2,3- dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidin-6-carboxylates at the treatment with alkyl halides, dimethyl sulfate, and diazomethane. Diazomethane alkylated the initial substrate at the oxygen atom of the carbonyl group of the thiazolidine fragment, the other reagents, at the oxygen atom of the hydroxyimino group.

About the authors

E. A. Lashmanova

Samara State Technical University

Author for correspondence.
Email: lashmanovaea@gmail.com
Russian Federation, Molodogvardeiskaya ul. 244, Samara, 443100

V. S. Larina

Samara State Technical University

Email: lashmanovaea@gmail.com
Russian Federation, Molodogvardeiskaya ul. 244, Samara, 443100

A. K. Shiryaev

Samara State Technical University

Email: lashmanovaea@gmail.com
Russian Federation, Molodogvardeiskaya ul. 244, Samara, 443100

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