Synthesis of cyclohexyl isovalerate by carbonylation of isobutylene with carbon monoxide and cyclohexanol in the presence of Pd(PPh3)4‒PPh3‒TsOH and its antimicrobial activity

Аннотация

A procedure has been developed for the synthesis of cyclohexyl isovalerate by reaction of isobutylene with carbon monoxide and cyclohexanol in the presence of the three-component catalytic system Pd(PPh₃)₄‒PPh₃‒TsOH. Cyclohexyl isovalerate showed a pronounced antibacterial activity.