Email this article Synthesis of new 2H-benzimidazole 1,3-dioxide derivatives analogous to separase inhibitor (Sepin-1)
- Authors: Chugunova E.A.1,2, Akylbekov N.I.3, Gaziev M.R.3, Samsonov V.A.4, Dobrynin A.B.1, Burilov A.R.1
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Affiliations:
- Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
- Kazan Federal University
- Kazan National Research Technological University
- Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch
- Issue: Vol 53, No 12 (2017)
- Pages: 1896-1898
- Section: Short Communications
- URL: https://journal-vniispk.ru/1070-4280/article/view/217087
- DOI: https://doi.org/10.1134/S1070428017120223
- ID: 217087
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Abstract
New biologically active 2H-benzimidazole 1,3-dioxide derivatives, analogs of Sepin-1, have been synthesized starting from benzofuroxan. Electrophilic substitution of hydrogen in the 2H-benzimidazole ring occurs at different positions, depending on the electrophile nature.
About the authors
E. A. Chugunova
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center; Kazan Federal University
Author for correspondence.
Email: elena-chugunova@list.ru
Russian Federation, ul. Arbuzova 8, Kazan, 420088 Tatarstan; ul. Kremlevskaya 18, Kazan, 420008 Tatarstan
N. I. Akylbekov
Kazan National Research Technological University
Email: elena-chugunova@list.ru
Russian Federation, ul. Karla Marksa 68, Kazan, 420015 Tatarstan
M. R. Gaziev
Kazan National Research Technological University
Email: elena-chugunova@list.ru
Russian Federation, ul. Karla Marksa 68, Kazan, 420015 Tatarstan
V. A. Samsonov
Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch
Email: elena-chugunova@list.ru
Russian Federation, pr. Akademika Lavrent’eva 9, Novosibirsk, 630090
A. B. Dobrynin
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: elena-chugunova@list.ru
Russian Federation, ul. Arbuzova 8, Kazan, 420088 Tatarstan
A. R. Burilov
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: elena-chugunova@list.ru
Russian Federation, ul. Arbuzova 8, Kazan, 420088 Tatarstan
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