Enviar artigo por via de e-mail Synthesis of Benzo[h]quinazolines from Ethyl 1-Amino-3-cyclohexyl-3,4-dihydronaphthalene-2-carboxylate
- Autores: Grigoryan N.P.1
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Afiliações:
- Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
- Edição: Volume 54, Nº 1 (2018)
- Páginas: 55-61
- Seção: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/217130
- DOI: https://doi.org/10.1134/S1070428018010049
- ID: 217130
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Resumo
The reaction of ethyl (2Z)-2-cyano-3-cyclohexylprop-2-enoate with benzylmagnesium chloride, followed by cyclization in the presence of sulfuric acid, provided an efficient method of synthesis of ethyl 1-amino-3-cyclohexyl-3,4-dihydronaphthalene-2-carboxylate which was converted to a number of new heterocyclic systems containing a benzo[h]quinazoline fragment.
Sobre autores
N. Grigoryan
Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
Autor responsável pela correspondência
Email: nver-55@mail.ru
Armênia, pr. Azatutyan 26, Yerevan, 0014
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