Synthesis and Antitubercular and Antibacterial Activities of Triethylammonium 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucopyranosyl Decyl Phosphate


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Abstract

Phosphorylation of 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucose at the anomeric hydroxy group gave previously unknown triethylammonium 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucopyranosyl phosphonate, and successive treatment of the latter with decan-1-ol and aqueous iodine afforded triethylammonium 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranosyl phosphate.

About the authors

B. F. Garifullin

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: kataev@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, 420088 Tatarstan

R. R. Sharipova

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: kataev@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, 420088 Tatarstan

A. D. Voloshina

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: kataev@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, 420088 Tatarstan

M. A. Kravchenko

Ural Research Institute of Phthisiopulmonology

Email: kataev@iopc.ru
Russian Federation, ul. 22 Parts”ezda 50, Yekaterinburg, 620039

V. E. Kataev

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Author for correspondence.
Email: kataev@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, 420088 Tatarstan

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