Bis-styrylquinazolinones Connected by Flexible Linkers

Аннотация

3,3′-(Ethane-1,2-diyl)-, 3,3′-(butane-1,4-diyl)-, 3,3′-hexane-1,6-diyl-, and 3,3′-[azanediylbis(ethane-2,1-diyl)]bis(2-methylquinazolin-4(3H)-ones) were synthesized by reactions of 2-methyl-4H-3,1-benzoxazin-4-one with ethane-1,2-diamine, butane-1,4-diamine, hexane-1,6-diamine, and N-(2-aminoethyl)ethane-1,2-di-amine, respectively, and their condensation with aromatic and heterocyclic aldehydes in acetic anhydride under reflux afforded the corresponding bis[2-[(E)-2-arylethenyl]quinazolin-4(3H)-ones].