Email this article Synthesis of Prolylproline
- Authors: Gaidukevich V.A.1, Popova L.A.1, Zubreichuk Z.P.1, Knizhnikov V.A.1
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Affiliations:
- Institute of Physical Organic Chemistry
- Issue: Vol 55, No 7 (2019)
- Pages: 1005-1008
- Section: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/220918
- DOI: https://doi.org/10.1134/S1070428019070169
- ID: 220918
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Abstract
Prolylproline has been synthesized by both classical peptide synthesis method utilizing tert-butoxycarbonyl or trifluoroacetyl protection of the NH group and carbodiimide-promoted peptide bond formation and by opening of the dioxopiperazine ring in octahydrodipyrrolo[1,2-a:1′,2′-d]pyrazine-5,10-dione obtained by thermolysis of proline methyl ester.
About the authors
V. A. Gaidukevich
Institute of Physical Organic Chemistry
Email: knizh@ifoch.bas-net.by
Belarus, Minsk
L. A. Popova
Institute of Physical Organic Chemistry
Email: knizh@ifoch.bas-net.by
Belarus, Minsk
Z. P. Zubreichuk
Institute of Physical Organic Chemistry
Email: knizh@ifoch.bas-net.by
Belarus, Minsk
V. A. Knizhnikov
Institute of Physical Organic Chemistry
Author for correspondence.
Email: knizh@ifoch.bas-net.by
Belarus, Minsk
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