Мақаланы E-mail арқылы жіберу Solvent-Free FeCl3-Assisted Electrophilic Fluorine-Catalyzed Knoevenagel Condensation to Yield α,β-Unsaturated Dicarbonyl Compounds and Coumarins
- Авторлар: Yang L.1,2, Zhu J.1,2,3, Xie F.1,2,3, Peng X.1,2, Lin B.1,2, Liu Y.1,2,3, Cheng M.1,2
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Мекемелер:
- Key Laboratory of Structure-Based Drug Design and Discovery
- Institute of Drug Research in Medicine Capital of China
- Wuya College of Innovation
- Шығарылым: Том 55, № 7 (2019)
- Беттер: 1053-1060
- Бөлім: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/220981
- DOI: https://doi.org/10.1134/S1070428019070236
- ID: 220981
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
A highly environmentally friendly procedure was developed for the Knoevenagel condensation of aromatic aldehydes with diethyl malonate in the presence of FeCl3 and N-fluorobenzenesulfonimide as a source of electrophilic fluorine under solvent-free conditions. The scope of the reaction was explored using commercially available substrates. The reaction with substituted salicylaldehydes afforded the corresponding coumarin derivatives which attract interest due to their potential medicinal importance.
Авторлар туралы
Lu Yang
Key Laboratory of Structure-Based Drug Design and Discovery; Institute of Drug Research in Medicine Capital of China
Email: mscheng@syphu.edu.cn
ҚХР, Shenyang; Benxi
Jiang Zhu
Key Laboratory of Structure-Based Drug Design and Discovery; Institute of Drug Research in Medicine Capital of China; Wuya College of Innovation
Email: mscheng@syphu.edu.cn
ҚХР, Shenyang; Benxi; Shenyang
Fukai Xie
Key Laboratory of Structure-Based Drug Design and Discovery; Institute of Drug Research in Medicine Capital of China; Wuya College of Innovation
Email: mscheng@syphu.edu.cn
ҚХР, Shenyang; Benxi; Shenyang
Xiaoshi Peng
Key Laboratory of Structure-Based Drug Design and Discovery; Institute of Drug Research in Medicine Capital of China
Email: mscheng@syphu.edu.cn
ҚХР, Shenyang; Benxi
Bin Lin
Key Laboratory of Structure-Based Drug Design and Discovery; Institute of Drug Research in Medicine Capital of China
Email: mscheng@syphu.edu.cn
ҚХР, Shenyang; Benxi
Yongxiang Liu
Key Laboratory of Structure-Based Drug Design and Discovery; Institute of Drug Research in Medicine Capital of China; Wuya College of Innovation
Хат алмасуға жауапты Автор.
Email: yongxiang.liu@syphu.edu.cn
ҚХР, Shenyang; Benxi; Shenyang
Maosheng Cheng
Key Laboratory of Structure-Based Drug Design and Discovery; Institute of Drug Research in Medicine Capital of China
Хат алмасуға жауапты Автор.
Email: mscheng@syphu.edu.cn
ҚХР, Shenyang; Benxi
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