Email this article Synthesis of 6I-O-(4-Methylbenzenesulfonyl)-β-cyclodextrin
- Authors: Novokshonov V.V.1, Xuan N.T.2, Shaglaeva N.S.2
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Affiliations:
- Favorskii Irkutsk Institute of Chemistry, Siberian Branch
- Irkutsk National Research Technical University
- Issue: Vol 55, No 10 (2019)
- Pages: 1616-1617
- Section: Short Communications
- URL: https://journal-vniispk.ru/1070-4280/article/view/221317
- DOI: https://doi.org/10.1134/S1070428019100245
- ID: 221317
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Abstract
An improved procedure has been proposed for the synthesis of 6I-O-(4-methylbenzenesulfonyl)-β-cyclodextrin by reaction of β-cyclodextrin with p-toluenesulfonyl chloride in aqueous alkali. Repeated use of unreacted p-toluenesulfonyl chloride and reduction of the volume of water by half in combination with optimized conditions make it possible to obtain the target product in up to 58% yield without loss of purity.
About the authors
V. V. Novokshonov
Favorskii Irkutsk Institute of Chemistry, Siberian Branch
Email: ShaglaevaNS@yandex.ru
Russian Federation, Irkutsk
Nguyen Thi Thu Xuan
Irkutsk National Research Technical University
Email: ShaglaevaNS@yandex.ru
Russian Federation, Irkutsk
N. S. Shaglaeva
Irkutsk National Research Technical University
Author for correspondence.
Email: ShaglaevaNS@yandex.ru
Russian Federation, Irkutsk
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