Email this article Aminomethylation of Thioureas with N,N-Dimethyl-1-(triethylsiloxy)methanamine, Involving Amino Group Exchange
- Authors: McMahon J.1, Sharma H.K.1, Metta-Magaña A.1, Pannell K.H.1
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Affiliations:
- Department of Chemistry
- Issue: Vol 55, No 11 (2019)
- Pages: 1764-1771
- Section: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/221405
- DOI: https://doi.org/10.1134/S1070428019110198
- ID: 221405
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Abstract
The O-triethylsilylated hemiaminal Et3SiOCH2NMe2 readily transfers the Me2NCH2-group to various thioureas under mild conditions and without catalysts or co-reagents. In the reaction with PhNHC(=S)·NHPh, the initially formed mono-substituted derivative PhNHC(=S)NPhCH2NMe2 readily rearranges to produce the unsymmetrical thiourea PhNHC(=S)NMe2 and hexahydro-1,3,5-triphenyl-1,3,5-triazine.
About the authors
J. McMahon
Department of Chemistry
Email: kpannell@utep.edu
United States, El Paso, Texas, 79968
H. K. Sharma
Department of Chemistry
Email: kpannell@utep.edu
United States, El Paso, Texas, 79968
A. Metta-Magaña
Department of Chemistry
Email: kpannell@utep.edu
United States, El Paso, Texas, 79968
K. H. Pannell
Department of Chemistry
Author for correspondence.
Email: kpannell@utep.edu
United States, El Paso, Texas, 79968
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