A One-Pot, Solvent-Free, and Catalyst-Free Synthesis of Substituted (E)-1-Phenyl-3-[2-(piperidin-1-yl)quinolin-3-yl]prop-2-en-1-ones Under Microwave Irradiation
- Authors: Pujari V.K.1, Vinnakota S.2, Kakarla R.K.2, Maroju S.1, Ganesh A.3
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Affiliations:
- NewAge life Science Pvt Ltd, IDA Phase-II
- Department of Chemistry
- Hypersynth Life Science, IDA Phase-II
- Issue: Vol 55, No 11 (2019)
- Pages: 1772-1776
- Section: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/221410
- DOI: https://doi.org/10.1134/S1070428019110204
- ID: 221410
Cite item
Abstract
A convenient one-pot, three-component, and solvent-free procedure for the preparation of substituted (E)-1-phenyl-3-[2-(piperidin-1-yl)quinolin-3-yl]prop-2-en-1-ones, which has made a significant improvement of previously reported methods, has been developed. The reaction of chloro aldehydes, ketones, and piperidine under microwave irradiation afforded the corresponding piperidine-substituted chalcone derivatives in high yields in shorter reaction times. All the synthesized compounds were characterized by IR and 1H and 13C NMR spectroscopy, and mass spectroscopy.
About the authors
V. K. Pujari
NewAge life Science Pvt Ltd, IDA Phase-II
Author for correspondence.
Email: pujarivijaykumar7@gmail.com
India, Mallapur, Hyderabad, Telangana
S. Vinnakota
Department of Chemistry
Email: pujarivijaykumar7@gmail.com
India, Donthanapally, Hyderabad, Telangana
R. K. Kakarla
Department of Chemistry
Email: pujarivijaykumar7@gmail.com
India, Medchal, Hyderabad, Telangana
S. Maroju
NewAge life Science Pvt Ltd, IDA Phase-II
Email: pujarivijaykumar7@gmail.com
India, Mallapur, Hyderabad, Telangana
A. Ganesh
Hypersynth Life Science, IDA Phase-II
Email: pujarivijaykumar7@gmail.com
India, Mallapur, Hyderabad, Telangana
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