Synthesis of New Guanidine-Containing Amphiphiles and Their Pyrene Analog for Liposomal Delivery Systems and Visualization in Target Cells
- Authors: Loseva A.A.1, Budanova U.A.1, Sebyakin Y.L.1
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Affiliations:
- Lomonosov Moscow Institute of Fine Chemical Technology
- Issue: Vol 55, No 12 (2019)
- Pages: 1826-1831
- Section: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/221441
- DOI: https://doi.org/10.1134/S1070428019120030
- ID: 221441
Cite item
Abstract
New cationic amphiphiles with a guanidine head group have been synthesized starting from lipoamino acids with the goal of creating drug and genetic material delivery systems. Their analog containing a pyrene fragment has also been obtained as a potential agent for visualization of liposome transport in various cells.
Keywords
About the authors
A. A. Loseva
Lomonosov Moscow Institute of Fine Chemical Technology
Email: c-221@yandex.ru
Russian Federation, Moscow, 119454
U. A. Budanova
Lomonosov Moscow Institute of Fine Chemical Technology
Author for correspondence.
Email: c-221@yandex.ru
Russian Federation, Moscow, 119454
Yu. L. Sebyakin
Lomonosov Moscow Institute of Fine Chemical Technology
Email: c-221@yandex.ru
Russian Federation, Moscow, 119454
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