Synthesis of New Guanidine-Containing Amphiphiles and Their Pyrene Analog for Liposomal Delivery Systems and Visualization in Target Cells


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Abstract

New cationic amphiphiles with a guanidine head group have been synthesized starting from lipoamino acids with the goal of creating drug and genetic material delivery systems. Their analog containing a pyrene fragment has also been obtained as a potential agent for visualization of liposome transport in various cells.

About the authors

A. A. Loseva

Lomonosov Moscow Institute of Fine Chemical Technology

Email: c-221@yandex.ru
Russian Federation, Moscow, 119454

U. A. Budanova

Lomonosov Moscow Institute of Fine Chemical Technology

Author for correspondence.
Email: c-221@yandex.ru
Russian Federation, Moscow, 119454

Yu. L. Sebyakin

Lomonosov Moscow Institute of Fine Chemical Technology

Email: c-221@yandex.ru
Russian Federation, Moscow, 119454

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