Oxidation of Thioamides to Amides with Tetrachloro- and Tetrabromoglycolurils

Abstract

Tetrabromo- and tetrachloroglycolurils have been shown to act as good oxidants capable of converting thioamides to the corresponding amides. This approach offers such advantages as good yields (81–99%), short reaction times (10–25 min), simple workup procedure, and environmental safety.