Email this article Reaction of Thioxanthylium Cation with Pharmacophoric Heterocyclic Amines
- Authors: Yunnikova L.P.1, Esenbaeva V.V.1, Danilova E.A.2, Islyaikin M.K.2
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Affiliations:
- Pryanishnikov Perm State Agro-Technological University
- Ivanovo State University of Chemistry and Technology
- Issue: Vol 55, No 12 (2019)
- Pages: 1985-1987
- Section: Short Communications
- URL: https://journal-vniispk.ru/1070-4280/article/view/221559
- DOI: https://doi.org/10.1134/S1070428019120327
- ID: 221559
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Abstract
Reactions of thioxanthylium tetrafluoroborate with pharmacophoric heterocyclic amines, pyrimidin-2-amine, 4,6-dimethylpyrimidin-2-amine, 2-aminopyrimidine-4,6-diol, and 1,3,4-thiadiazole-2,5-diamine, gave stable products of electrophilic substitution of one hydrogen atom per amino group. The product structure was confirmed by 1H NMR and mass spectra and X-ray analysis of N-(9H-tmoxanthen-9-yl)pyrimidin-2-amine.
About the authors
L. P. Yunnikova
Pryanishnikov Perm State Agro-Technological University
Author for correspondence.
Email: yunnikova@yahoo.com
Russian Federation, Perm, 614990
V. V. Esenbaeva
Pryanishnikov Perm State Agro-Technological University
Email: yunnikova@yahoo.com
Russian Federation, Perm, 614990
E. A. Danilova
Ivanovo State University of Chemistry and Technology
Email: yunnikova@yahoo.com
Russian Federation, Ivanovo, 153000
M. K. Islyaikin
Ivanovo State University of Chemistry and Technology
Email: yunnikova@yahoo.com
Russian Federation, Ivanovo, 153000
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