Email this article Metallomicellar Complex of 1-Hexadecyl-4-aza-1-azoniabicyclo-[2.2.2]octane Bromide with Copper Dibromide for Solubilization of Nitrofurantoin
- Authors: Zhil’tsova E.P.1, Ibatullina M.R.2, Lukashenko S.S.1, Kutyreva M.P.2, Zakharova L.Y.1
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Affiliations:
- Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
- Kazan (Volga Region) Federal University
- Issue: Vol 54, No 3 (2018)
- Pages: 431-435
- Section: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/217313
- DOI: https://doi.org/10.1134/S1070428018030107
- ID: 217313
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Abstract
Associates of amphiphilic 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide–copper dibromide complex solubilize nitrofurantoin (furadonin). The solubilizing capacity of premicellar aggregates with respect to nitrofurantoin is 15 times higher than that of micelles and is considerably higher (by a factor of 5–16) than the solubilizing effect of micellar solutions of the complex, ligand, and conventional cationic surfactants with respect to Orange OT.
About the authors
E. P. Zhil’tsova
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Author for correspondence.
Email: Zhiltsova@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
M. R. Ibatullina
Kazan (Volga Region) Federal University
Email: Zhiltsova@iopc.ru
Russian Federation, ul. Kremlevskaya 18, Kazan, Tatarstan, 420008
S. S. Lukashenko
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: Zhiltsova@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
M. P. Kutyreva
Kazan (Volga Region) Federal University
Email: Zhiltsova@iopc.ru
Russian Federation, ul. Kremlevskaya 18, Kazan, Tatarstan, 420008
L. Ya. Zakharova
Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
Email: Zhiltsova@iopc.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420088
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