Modified Hantzsch reaction in the presence of chiral organic catalysts

Аннотация

Modified Hantzsch reaction in three- and four-component system in the presence of new chiral organic catalysts was investigated and the advantages of this reaction in three-component system compared to four-component one were demonstrated, the influence of catalysts on the dynamics and stereochemistry of the reaction was elucidated. The enantiomeric excess of the main reaction product was evaluated with HPLC, its structure was proved by X-ray diffraction analysis.