Chemical Transformations of 2-(3-Aryl-4-nitrobutanoyl)-5,5-dimethylcyclohexane-1,3-diones: II. Synthesis of New 6,7-Dihydro-1,2-benzoxazol-4(5H)-ones with Functionalized Side Chain

Аннотация

Transformation of the nitromethyl group in 3-(2-aryl-3-nitropropyl)-6,6-dimethyl-6,7-dihydro-1,2-benzoxazol-4(5H)-ones by the Nef reaction gave the corresponding aldehydes. Jones oxidation of the latter afforded carboxylic acids together with oxidative decarboxylation products. The possibility for the construction of heterocyclic fragment on the basis of the formyl or carboxylmethyl group of the resulting 6,7-dihydro-1,2-benzoxazol-4(5H)-one derivatives was studied.