Chemical Transformations of 2-(3-Aryl-4-nitrobutanoyl)-5,5-dimethylcyclohexane-1,3-diones: II. Synthesis of New 6,7-Dihydro-1,2-benzoxazol-4(5H)-ones with Functionalized Side Chain
- Авторы: Pashkovskii F.S.1, Dontsu Y.S.1, Rubinov D.B.1, Lakhvich F.A.1
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Учреждения:
- Institute of Bioorganic Chemistry
- Выпуск: Том 54, № 6 (2018)
- Страницы: 844-854
- Раздел: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/218043
- DOI: https://doi.org/10.1134/S1070428018060040
- ID: 218043
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Аннотация
Transformation of the nitromethyl group in 3-(2-aryl-3-nitropropyl)-6,6-dimethyl-6,7-dihydro-1,2-benzoxazol-4(5H)-ones by the Nef reaction gave the corresponding aldehydes. Jones oxidation of the latter afforded carboxylic acids together with oxidative decarboxylation products. The possibility for the construction of heterocyclic fragment on the basis of the formyl or carboxylmethyl group of the resulting 6,7-dihydro-1,2-benzoxazol-4(5H)-one derivatives was studied.
Об авторах
F. Pashkovskii
Institute of Bioorganic Chemistry
Автор, ответственный за переписку.
Email: pashkovsky61@mail.ru
Белоруссия, ul. Akademika Kuprevicha 5/2, Minsk, 220141
Yu. Dontsu
Institute of Bioorganic Chemistry
Email: pashkovsky61@mail.ru
Белоруссия, ul. Akademika Kuprevicha 5/2, Minsk, 220141
D. Rubinov
Institute of Bioorganic Chemistry
Email: pashkovsky61@mail.ru
Белоруссия, ul. Akademika Kuprevicha 5/2, Minsk, 220141
F. Lakhvich
Institute of Bioorganic Chemistry
Email: pashkovsky61@mail.ru
Белоруссия, ul. Akademika Kuprevicha 5/2, Minsk, 220141
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