Efficient synthesis of cyclophanes containing sulfur and nitrogen atoms by cycloaminomethylation of benzenedithiols in the presence of samarium-based catalysts

Resumo

An efficient procedure has been developed for the synthesis of 3-aryl-3,4-dihydro-2H-1,5,3-benzodithiazepines, 4-aryl-2,6-dithia-4-azabicyclo[5.3.1]undeca-1(11),7,9-trienes, and 4,10,16-triaryl-2,6,8,12,14,18-hexathia-4,10,16-triaza-1,7,13(1,4)-tribenzenacyclooctadecaphanes by samarium-catalyzed cycloaminomethylation of benzenedithiols with N,N-bis(methoxymethyl)anilines.