Deamination of 3-(dialkylamino)-1,4-diarylhex-5-en-1-ynes during vacuum distillation
- Autores: Chukhajian E.O.1, Shahkhatuni К.G.1, Chukhajian E.O.1, Ayrapetyan L.V.1, Panosyan G.A.1
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Afiliações:
- Scientific and Technological Center of Organic and Pharmaceutical Chemistry
- Edição: Volume 53, Nº 2 (2017)
- Páginas: 178-183
- Seção: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/215736
- DOI: https://doi.org/10.1134/S1070428017020063
- ID: 215736
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Resumo
During vacuum distillation of 3-(dialkylamino) derivatives of 1,4-diphenyl- and 4-phenyl-1-(p-chlorophenyl) hex-5-en-1-ynes deamination occurs resulting in a high yield of p-diarylbenzenes. The amines transformation into terbenzenes is a domino-reaction: first step consists in the β-elimination of secondary amines with the generation of conjugated dienyne which via an electrocyclic reaction transforms into cyclic allene intermediate. The latter after 1,3- or 1,5-hydride shift quickly converts into the final reaction products.
Sobre autores
E. Chukhajian
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: qnarsh@yandex.ru
Armênia, pr. Azatutyana 26, Yerevan, 0014
К. Shahkhatuni
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: qnarsh@yandex.ru
Armênia, pr. Azatutyana 26, Yerevan, 0014
El. Chukhajian
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: qnarsh@yandex.ru
Armênia, pr. Azatutyana 26, Yerevan, 0014
L. Ayrapetyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: qnarsh@yandex.ru
Armênia, pr. Azatutyana 26, Yerevan, 0014
G. Panosyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Autor responsável pela correspondência
Email: qnarsh@yandex.ru
Armênia, pr. Azatutyana 26, Yerevan, 0014
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