Is it possible to identify compliance and adherence to therapy? Experts opinion

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Abstract

Today, the terms “compliance and adherence” are often used in the medical literature. The problem of patient compliance/adherence to therapy is the basis of the physician–patient relationship complex. The study of this complex is used by specialists with various profiles to assess the effectiveness of therapy. This publication has studied the opinion of specialists when answering the following question: “Is it possible to identify compliance and adherence to therapy?” The factors determining the compliance/adherence of patients to treatment regardless of nosological forms of the disease are systematized. A total of four groups of factors of nonadherence to therapy associated with the disease, patient, doctor, and treatment were identified in this study.

About the authors

Tatiana V. Sokolova

Moscow State University of Food Production

Email: stv_morf2005@mail.ru
ORCID iD: 0000-0002-5450-4218
Russian Federation, Moscow

M. S. Davidenko

Moscow State University of Food Production

Email: 2236779@mail.ru
ORCID iD: 0000-0001-9999-5244
Russian Federation, Moscow

Alеxandr P. Malyarchuk

Moscow State University of Food Production

Author for correspondence.
Email: 2236779@mail.ru
ORCID iD: 0000-0003-2559-846X

MD, PhD, DSc, Professor of the Department of Skin and Venereal Diseases with a Cosmetology Course of
Medical Institute of Continuing Education of Moscow State University of Food Production

Russian Federation, Moscow

References

  1. Adherence to long-term therapies: evidence for action. World Health Organization; 2003. Available at: http://www.who.int/chp/knowledge/publications/adherence/report/en/ (accessed: 06 Apr 2013).
  2. Khoseva EN, Morozova TE, Andrushina TB. Efficacy and safety of modern medicines in the prism opinion of patients. Clinical Pharmacology and Therapy. Russian Journal. 2012;21(1):30-4. (in Russian)
  3. Sirota NA, Yaltonsky VM, Moskvichenko DV. Psychological factors of adherence to treatment in patients with breast cancer. Remedium. Russian Journal. 2015;(11):16-20. (in Russian)
  4. Danilov DS. Therapeutic collaboration (compliance): Content of the definition, mechanisms of formation, and methods of optimization. Neurology, Neuropsychiatry, Psychosomatics. Russian Journal. 2014;(2):4-12. (in Russian)
  5. Elfimova EV, Elfimov MA. Personality and disease: the «internal picture of the disease», quality of life and commitment. Deputy Chief Physician. Russian Journal. 2009;11:18-25. (in Russian)
  6. Kagramanyan IN. Evidence-based medicine and actual clinical practice. Journal of Volgograd State Medical University. Russian Journal. 2015;54(2):18-26. (in Russian)
  7. Kvitchataya AI, Piminov AF. High compliance as factor in the effectiveness of treatment. Apteka. Russian Journal. 2012; 871(50):21-4. (in Russian)
  8. Montes Rosel’ KV, Sokolova TV, Malyarchuk AP. Adherence to treatment for dermatophytes of the feet: the Union of the doctor and the patient. Problems in Medical Mycology. Russian Journal. 2019;21(2):105. (in Russian)
  9. Pimanov SI, Dikareva EA, Makarenko EV. Adherence to the pharmacotherapy is a necessary condition for effective treatment. Medical Business. Russian Journal. 2014;5(39):47-52. (in Russian)
  10. Starodubov VI, Kagramanyan IN, Khokhlov AL. Compliance problems in the light of medical technology assessment. Assessment of medical technology: international experience. Moscow: Association of International Pharmaceutical Manufacturers; 2012:101-12. (in Russian)
  11. Chukaeva II. What is Compliance and what can we do to improve it? Medical Business. Russian Journal. 2012;(2):21-6. (in Russian)
  12. Melnikow J, Kiefe C. Patient compliance and medical research: issues in methodology. J Gen Inter Med. 1994;9(2):96-105.
  13. Goldsmith CH. The effect of compliance distributions on therapeutic trials. In: Haynes RB, Taylor DW, Sackett DL, eds. Compliance in HealthCare. Baltimore: John Hopkins University Press; 1979:63-77.
  14. Donovan JL, Blake DR. Patient non-compliance: deviance or reasoned decision making? Soc Sci Med. 1992;34(5):507-13.
  15. DiMatteo MR. Variations in patients’ adherence to medical recommendations: a quantitative review of 50 years of research. Med Care. 2004;42(3):200-9.
  16. Konradi AO. The importance of adherence to therapy in the treatment of cardiac diseases. Directory of a polyclinic doctor. Russian Journal. 2007;(6):8-12. (in Russian)
  17. Konradi AO, Polunicheva EV. Lack of adherence to the treatment of hypertension: causes and correction. Arterial Hypertension. Russian Journal. 2004;10(3):137-43. (in Russian)
  18. Kots YaI, Mitrofanova IS. New ways of enhancing the efficiency of treatment for chronic heart failure. Medical Journal of the Russian Federation. 2007;(4):4-7. (in Russian)
  19. Oganov RG, Gilyarevsky SR. How to improve adherence to the treatment of a patient with arterial hypertension. Zdorovie Ukrainy. 2008;(9):47-9. (in Russian)
  20. Pogosova GV, Koltunov IE, Roslavtseva AN. Compliance to treatment of arterial hypertension and ischemic heart disease – key condition of lowering of cardiovascular mortality. Cardio- logy. Russian Journal 2007;(3):79-84. (in Russian)
  21. Surkova EV, Melnikova OG. Some aspects of commitment to medicine therapy in patients with type 2 diabetes. Difficult Patient. Russian Journal. 2008;6(11):35-8. (in Russian)
  22. Zinchenko YuP, Pervichko EI, Shmelev EI, Shmeleva NM. Problematic compliance in medicine: the view of a clinical psychologist (experience of clinical and psychological research of compliance in patients with chronic obstructive pulmonary disease). In: Materials of the all-Russian scientific and practical conference with international participation ”Clinical psychology in healthcare and education”. Moscow, 24-25 Nov 2011. Moscow: Moscow State Medical and Dental University; 2011:13-9. Available at: http://medpsy.ru/library/library105.pdf (in Russian)
  23. Delaryu VV, Yudin SA, Borzenko AS. Compliance of tuberculosis patients (according to comparative analysis). Medicinskaâ psihologiâ v Rossii. Russian Journal. 2013;4(21). Available at: http://mprj.ru/archiv_global/2013_4_21/nomer/nomer12.php (accessed: 14.06.2018). (in Russian)
  24. Pyanzova TV. Psychological predictors of low compliance among new cases of pulmonary tuberculosis. Bulletin of Siberian Medicine. Russian Journal. 2012;6:216-217. (in Russian)
  25. Banshchikov FR. Compliance in Psychiatry: Reality and Prospects. Review of psychiatry and medical psychology. Russian Journal. 2006;(4):9-11. (in Russian)
  26. Lutova NB, Neznanov NG, Vid VD. Compliance in psychiatry and how to evaluate it. Psychiatry and psychopharmacotherapy. Russian Journal. 2008;10(1):8-12. (in Russian)
  27. Afanasenkova TE. General practitioner’s assessment of compliance and mental status in erosive gastritis patients. Bulletin of the Smolensk State Medical Academy. Russian Journal. 2012;(1):37-9. (in Russian)
  28. Kotov AS. Compliance in patients with epilepsy. Russian Journal of neurology and psychiatry. 2010;(11):46-8. (in Russian)
  29. Grillo M, Gassner L, Marshman G, Dunn S, Hudson P. Pediatric Atopic Eczema: The Impact of an Education Intervention. Pediatric Dermatol. 2006;23(5):428-36.
  30. Babanov SA. The problem of compliance using modern antifungal drugs. Consilium Medicum. Dermatology. Russian Journal. 2013;(1):7-9. (in Russian)
  31. Gorlanov IA, Mikirtichan GL, Zaslavskiy DV, Kaurova TV, Murashkin NN. Clinical and social problems of compliance in pediatric dermatology. Herald of Venerology and Dermatology. Russian Journal. 2011;(1):36-40. (in Russian)
  32. Kochergin NG. Psoriasis: compliance and calcipotriol + betamethazone dipropionate. Clinical Dermatology and Venereology. Russian Journal. 2010;8(3):42-6. (in Russian)
  33. Kungurov NV, Kokhan MM, Kurilko ON, Zhukova TN, Keniksfest YuV, Ivashkevich AG, et al. Acne as a medical and social problem of youth. Ural Medical Journal. Russian Journal. 2004;3:4-8. (in Russian)
  34. Lytkina EA, Potekaev NN, Bilalova UG, Kochergin NG, Chernikova EA. The quality of life of the patients presenting with atopic dermatitis and their compliance with external therapy. Russian Journal of Clinical Dermatology and Venereology. 2011;(1):45-8. (in Russian)
  35. Martynov AA, Spiridonova EV, Butareva MM. Increasing compliance to treatment and rehabilitation programs in patients in hospitals, outpatient and policlinic departments, and factors having an effect on compliance. Herald of Venerology and Dermatology. Russian Journal. 2012;(1):21-7. (in Russian)
  36. Shakirova AT. The impact of compliance on the effectiveness of treatment and quality of life, in young patients with moderate and severe acne. International Journal of Applied and Fundamental Research. 2017;(2):33-7. (in Russian)
  37. Ushakov DN, ed. Explanatory dictionary of the Russian language. Moscow: State Institute of the Soviet Encyclopedia; 1935-1940. (in Russian)
  38. Ozhegov SI, Shvedova NYu. Explanatory dictionary of the Russian language. Russian Academy of Sciences. Vinogradov Institute of Russian language. Moscow: Azbukovnik; 1997. (in Russian)
  39. Sackett DL. Introduction and the magnitude of compliance and noncompliance In: Compliance with therapeutic regimens. Baltimore: Johns Hopkins University Press; 1976.
  40. Compact Oxford Russian Dictionary. Oxford University Press; 2013.
  41. Horne R. Compliance, adherence, and concordance: implications for asthma treatment. Chest. 2006;130(1, Suppl):S65-72.
  42. Saverskaya EN, Montes Rosel KV, Malyarchuk AP, Sokolova TV, Gura OV. Analysis of factors influencing the adherence of patients with foot mycosis to therapy. Advances in Medical Mycology. 2017:88-91. (in Russian)
  43. Dzhakubekova AU, Kazymbekov KR. Current state of the problem of patient’s addition to treatment (review). Bulletin of the Kyrgyz State Medical Academy IK Ahunbaeva. Bishkek: KGMA. 2012;(4):42-7. (in Russian)
  44. Grigoryan NA. Analysis of the ambulator’s patients adherence to antibiotic treatment. Bulletin of Medical Internet Conferences. Russian Journal. 2017;7(1):447. (in Russian)
  45. Keating NL, Gandhi TK, Orav EJ, Bates DW, Ayanian JZ. Patient characteristics and experiences associated with trust in specialist physicians. Arch Intern Med. 2004;164(9):1015-20.
  46. Gladko VV, Saverskaya EN, Montes Rosel KV, Sokolova TV, Malyarchuk AP, Golovinov AI, Panchenko L. Compliance as one of the problems of rational pharmacotherapy of dermatophytosis of the feet. Medical Bulletin of the Ministry of Internal Affairs. Russian Journal. 2019;(3):74-9. (in Russian)
  47. Mosolov SN. The current stage of development of psychopharmacotherapy. Russian Medical Journal. 2002;10(12-13):45-9. (in Russian)
  48. Belousov YuB, Moiseev VS, Lepakhin VK. Clinical pharmacology and pharmacotherapy. Guide for doctors. Moscow: Universum publishing; 1997. (in Russian)
  49. Nunes V, Neilson J, Flynn N. Clinical guidelines and evidence review for medicines: involving patients in decisions about prescribed medicines and supporting adherence. London: National Collaborating Centre for Primary Care and Royal College of General Practitioners; 2009.
  50. Simpson SH, Eurich DT, Majumdar SR, Padwal RS, Tsuyuki RT, Varney J, Johnson JA. A meta-analysis of the association between adherence to drug therapy and mortality. Br Med J. 2006; 33(7557):15-8.
  51. Wa van der MH, Jaarsma T. Adherence in heart failure in the elderly: problem and possible solutions. Int J Cardiol. 2008;125(2):203-8.
  52. Naumova EA, Shvarts YuG. Implementation by patients of medical appointments: are interventions aimed at improving this indicator effective. International Journal of Medical Practice. 2006;(1):48-60. (in Russian)
  53. Soldatchenko SS, Donich SG, Ignatonis IP. Adherence to the treatment of patients with bronchial asthma: current status of the issue. Ukrainian Pulmonology Journal. 2008;(2):35-8. (in Russian)
  54. Zaychenko AV, Pasichnichenko VA, Bogdanova TA. Pharmaceutical custody in topical therapy: muscular-joint pain and fungal skin lesions. Apteka. 2012;866(45). Available at: https://www.apteka.ua/article/172093 (accessed: 19.11.2012). (in Russian)
  55. Kalugin IV, Khaustova EA. The problem of compliance in gerontopsychiatric patients. Arkhiv Psikhiatrii. 2016;22(4):20-8. (in Russian)
  56. Waeber B, Burrier M, Brunner HR. How to improve adherence with prescribed treatment in hypertensive patients? Cardiovase Pharmacol. 2000;36(3):23-6.
  57. Svensson S, Kjellgren KI, Ahlner J. Reasons for adherence with antihypertensive medication. Int J Cardiol. 2000;76(2-3):157-63.
  58. Charman CR, Morris AD, Williams HC. Topical corticosteroid phobia in patients with atopic eczema. Br J Dermatol. 2000;142(5):931-6.
  59. Jokisalo E, Enlund H, Halonen P, Takala J, Kumpusalo E. Factors related to poor control of blood pressure with antihypertensive drug therapy. Blood Press. 2003;12(1):49-55.
  60. Choi WJ, Kim BR, Youn SW. Adherence to topical therapies for the treatment of psoriasis: Surveys of Physicians and Patients. Ann Dermatol. 2017;29(5):559-64.
  61. Hong CH, Papp KA, Lophaven KW, Skallerup P, Philipp S. Patients with psoriasis have different preferences for topical therapy, highlighting the importance of individualized treatment approaches: randomized phase IIIb PSO-INSIGHTFUL study. J Eur Acad Dermatol Venerol. 2017;31(11):1876-83.

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