Email this article Genomic and proteomic profiles of Acholeplasma laidlawii strains differing in sensitivity to ciprofloxacin
- Authors: Medvedeva E.S.1,2, Davydova M.N.1, Mouzykantov A.A.1,2, Baranova N.B.1,2, Grigoreva T.Y.1, Siniagina M.N.2, Boulygina E.A.2, Chernova O.A.1,2, Chernov V.M.1,2
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Affiliations:
- Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center
- Kazan (Volga Region) Federal University
- Issue: Vol 466, No 1 (2016)
- Pages: 23-27
- Section: Biochemistry, Biophysics and Molecular Biology
- URL: https://journal-vniispk.ru/1607-6729/article/view/210978
- DOI: https://doi.org/10.1134/S1607672916010075
- ID: 210978
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Abstract
As a result of comparative analysis of complete genomes as well as cell and vesicular proteomes of A. laidlawii strains differing in sensitivity to ciprofloxacin, it was first shown that the mycoplasma resistance to the antibiotic is associated with the reorganization of genomic and proteomic profiles, which concerns many genes and proteins involved in fundamental cellular processes and realization of bacterial virulence.
About the authors
E. S. Medvedeva
Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University
Author for correspondence.
Email: elena-med@list.ru
Russian Federation, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111; ul. Kremlevskaya 18, Kazan Tatarstan, 420008
M. N. Davydova
Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center
Email: elena-med@list.ru
Russian Federation, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111
A. A. Mouzykantov
Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University
Email: elena-med@list.ru
Russian Federation, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111; ul. Kremlevskaya 18, Kazan Tatarstan, 420008
N. B. Baranova
Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University
Email: elena-med@list.ru
Russian Federation, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111; ul. Kremlevskaya 18, Kazan Tatarstan, 420008
T. Yu. Grigoreva
Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center
Email: elena-med@list.ru
Russian Federation, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111
M. N. Siniagina
Kazan (Volga Region) Federal University
Email: elena-med@list.ru
Russian Federation, ul. Kremlevskaya 18, Kazan Tatarstan, 420008
E. A. Boulygina
Kazan (Volga Region) Federal University
Email: elena-med@list.ru
Russian Federation, ul. Kremlevskaya 18, Kazan Tatarstan, 420008
O. A. Chernova
Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University
Email: elena-med@list.ru
Russian Federation, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111; ul. Kremlevskaya 18, Kazan Tatarstan, 420008
V. M. Chernov
Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University
Email: elena-med@list.ru
Russian Federation, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111; ul. Kremlevskaya 18, Kazan Tatarstan, 420008
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