Analysis of immune–biochemical indicators to assess the risk of developing cardiological pathology


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

Prognostic immuno-biochemical tests to assess the severity of the condition of patients with cardiac diseases were developed. A comparative analysis of clinical and laboratory blood parameters, which are used in practice for the diagnosis and prognosis of diseases, and an analysis of the content of natural antibodies (n-Abs) to β-endorphin, bradykinin, histamine, dopamine, and serotonin were performed. A significant correlation between the level of n-Abs, the main biochemical parameters, and the content of blood corpuscles was revealed. The practical importance of the combined use of immunological and biochemical tests to increase the reliability of prediction of the severity of heart pathologies was established.

About the authors

V. S. Morozova

Institute of Physiologically Active Compounds

Author for correspondence.
Email: vmorozova@gmail.com
Russian Federation, Chernogolovka, Moscow oblast, 142432

I. A. Moseikin

Russian Medical Academy of Postgraduate Education

Email: vmorozova@gmail.com
Russian Federation, Moscow, 123995

S. N. Petrochenko

Institute of Physiologically Active Compounds

Email: vmorozova@gmail.com
Russian Federation, Chernogolovka, Moscow oblast, 142432

M. A. Myagkova

Institute of Physiologically Active Compounds

Email: vmorozova@gmail.com
Russian Federation, Chernogolovka, Moscow oblast, 142432

L. F. Panchenko

Research Institute of General Pathology and Pathophysiology

Email: vmorozova@gmail.com
Russian Federation, Moscow, 125315

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2017 Pleiades Publishing, Ltd.