Changes in levels of metabolic pathway gene expression under conditions of clear cell renal carcinoma

V. Yu. Bashmakov; T. M. Gorbacheva; A. V. Panevina; S. A. Solodskikh; I. P. Moshurov; A. A. Mikhaylov; A. Yu. Maslov; V. N. Popov

doi:10.1134/S1607672917030024

Changes in levels of metabolic pathway gene expression under conditions of clear cell renal carcinoma

Authors: Bashmakov V.Y.¹, Gorbacheva T.M.¹, Panevina A.V.¹, Solodskikh S.A.¹, Moshurov I.P.², Mikhaylov A.A.², Maslov A.Y.¹, Popov V.N.¹
Affiliations:
1. Department of Genetics, Cytology, and Bioengineering
2. Voronezh Regional Clinical Oncological Dispensary
Issue: Vol 474, No 1 (2017)
Pages: 159-161
Section: Biochemistry, Biophysics, and Molecular Biology
URL: https://journal-vniispk.ru/1607-6729/article/view/211888
DOI: https://doi.org/10.1134/S1607672917030024
ID: 211888

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Abstract

A whole-transcriptome analysis of gene expression in six samples of clear cell renal cancer was performed. Using bioinformatics methods, we established a relationship between gene expression data and changes in activity of metabolic pathways: in this cancer type, the expression of genes involved in the metabolism of carbohydrates, lipids, and amino acids as well as in energy metabolism changed most significantly.