Kinetics of DNA elongation


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Abstract

A mathematical model of the DNA elongation stage is proposed, and a formula for calculating the characteristic time of doubling a DNA strand consisting of a large numbers of nucleotides was derived. It is shown that, when the number of nucleotides is greater than 50, it is fair to use a linear dependence of the elongation time on the number of nucleotides. Calculations of the DNA elongation time for a number of organisms are given.

About the authors

V. I. Bykov

Emanuel Institute of Biochemical Physics

Email: luks@list.ru
Russian Federation, Moscow, 117977

A. V. Lukovenkov

Emanuel Institute of Biochemical Physics

Author for correspondence.
Email: luks@list.ru
Russian Federation, Moscow, 117977

S. D. Varfolomeev

Emanuel Institute of Biochemical Physics

Email: luks@list.ru
Russian Federation, Moscow, 117977

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