Messenger RNA of the Histidine-Rich Glycoprotein in Breast Tumors


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Abstract

The content of mRNA of the histidine-rich glycoprotein (HRG), a potential marker of malignant neoplasia, which can be used in differential diagnosis of breast tumors, was determined in 110 breast tumor biopsy samples. The presence of HRG mRNA did not depend on the cancer type, on the preoperative treatment or its absence, as well as on the tumor progression stage and the presence of metastases.

About the authors

A. I. Autenshlyus

Ministry of Healthcare of the Russian Federation; Research Institute of Molecular Biology and Biophysics

Author for correspondence.
Email: lpciip@211.ru
Russian Federation, Novosibirsk, 630091; Novosibirsk, 630117

I. I. Brusentsov

Ministry of Healthcare of the Russian Federation; Federal Research Center Institute of Cytology and Genetics, Siberian Branch

Email: lpciip@211.ru
Russian Federation, Novosibirsk, 630091; Novosibirsk, 630090

I. O. Marinkin

Ministry of Healthcare of the Russian Federation

Email: lpciip@211.ru
Russian Federation, Novosibirsk, 630091

S. A. Smirnova

JSC Vector-Best

Email: lpciip@211.ru
Russian Federation, Kol’tsovo, Novosibirsk oblast, 633159

M. Yu. Rukavishnikov

JSC Vector-Best

Email: lpciip@211.ru
Russian Federation, Kol’tsovo, Novosibirsk oblast, 633159

V. V. Lyakhovich

Research Institute of Molecular Biology and Biophysics

Email: lpciip@211.ru
Russian Federation, Novosibirsk, 630117

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