Mathematical Modeling of Open States in DNA Molecule Depending on the Deuterium Concentration in the Surrounding Liquid Media at Different Values of Hydrogen Bond Disruption Energy

S. S. Dzhimak; M. I. Drobotenko; A. A. Basov; A. A. Svidlov; L. V. Fedulova; O. M. Lyasota; M. G. Baryshev

doi:10.1134/S1607672918060169

Mathematical Modeling of Open States in DNA Molecule Depending on the Deuterium Concentration in the Surrounding Liquid Media at Different Values of Hydrogen Bond Disruption Energy

Authors: Dzhimak S.S.¹, Drobotenko M.I.¹, Basov A.A.¹^,2, Svidlov A.A.¹, Fedulova L.V.³, Lyasota O.M.¹, Baryshev M.G.¹
Affiliations:
1. Kuban State University
2. Kuban State Medical University
3. Gorbatov Federal Research Center of Food Systems
Issue: Vol 483, No 1 (2018)
Pages: 359-362
Section: Biochemistry, Biophysics, and Molecular Biology
URL: https://journal-vniispk.ru/1607-6729/article/view/212613
DOI: https://doi.org/10.1134/S1607672918060169
ID: 212613

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Abstract

The effect of the deuterium concentration in the surrounding liquid medium on the appearance of open states between the nitrogen bases of a double-stranded DNA molecule was investigated. It is shown that the nature of this effect depends on the magnitude of the energy of the hydrogen bond break.