The CYP443C1 (CYP74 clan) Cytochrome of Sea Anemone Nematostella vectensis–the First Metazoan Enzyme Possessing Hydroperoxide Lyase/Epoxyalcohol Synthase Activity


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Abstract

A novel CYP74 clan gene CYP443С1 of the starlet sea anemone (Nematostella vectensis, Cnidaria) has been cloned, and the properties of the corresponding recombinant protein have been studied. Depending on the substrate, CYP443С1 exhibited double function hydroperoxide lyase/epoxyalcohol synthase activity.

About the authors

S. S. Gorina

Kazan Institute of Biochemistry and Biophysics,
FRC Kazan Scientific Center of RAS

Author for correspondence.
Email: gsvetlana87@gmail.com
Russian Federation, Kazan, Tatarstan, 420111

Y. Y. Toporkova

Kazan Institute of Biochemistry and Biophysics,
FRC Kazan Scientific Center of RAS

Email: gsvetlana87@gmail.com
Russian Federation, Kazan, Tatarstan, 420111

L. S. Mukhtarova

Kazan Institute of Biochemistry and Biophysics,
FRC Kazan Scientific Center of RAS

Email: gsvetlana87@gmail.com
Russian Federation, Kazan, Tatarstan, 420111

A. N. Grechkin

Kazan Institute of Biochemistry and Biophysics,
FRC Kazan Scientific Center of RAS

Email: gsvetlana87@gmail.com
Russian Federation, Kazan, Tatarstan, 420111

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