Email this article The Induction of the Synthesis of Interferon, CD4 and CD8 T Lymphocytes in Blood and Spleen of Mice after Oral Vaccination with the “Early” Protein HPV16 E2
- Authors: Salyaev R.K.1,2, Rekoslavskaya N.I.1,2, Stolbikov A.S.1,2
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Affiliations:
- Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch, Russian Academy of Sciences
- Irkutsk Scientific Center, Siberian Branch, Russian Academy of Sciences
- Issue: Vol 488, No 1 (2019)
- Pages: 316-319
- Section: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journal-vniispk.ru/1607-6729/article/view/213084
- DOI: https://doi.org/10.1134/S1607672919050077
- ID: 213084
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Abstract
High contents of interferon and CD4 and CD8 T lymphocytes were found in blood and spleen cells of mice after their oral vaccination with the “early” protein of HPV16 E2 by using ELISPOT, Western blot hybridization, and enzyme immunoassay technique. It was concluded that the “early” protein HPV16 E2 is involved in the immune system activation during control of pathogenesis and neoplasia.
About the authors
R. K. Salyaev
Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch, Russian Academy of Sciences; Irkutsk Scientific Center, Siberian Branch,Russian Academy of Sciences
Author for correspondence.
Email: salyaev@sifibr.irk.ru
Russian Federation, Irkutsk; Irkutsk
N. I. Rekoslavskaya
Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch, Russian Academy of Sciences; Irkutsk Scientific Center, Siberian Branch,Russian Academy of Sciences
Author for correspondence.
Email: rekoslavskaya@sifibr.irk.ru
Russian Federation, Irkutsk; Irkutsk
A. S. Stolbikov
Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch, Russian Academy of Sciences; Irkutsk Scientific Center, Siberian Branch,Russian Academy of Sciences
Email: rekoslavskaya@sifibr.irk.ru
Russian Federation, Irkutsk; Irkutsk
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