THE POSSIBILITY OF USING ANTIBIOTIC AND ENZYME ELECTROPHORESIS FOR THE COMBINED TREATMENT OF CHRONIC HEMATOGENIC OSTEOMYELITIS IN THE CHILDREN

This study was designed to examine and treat 40 children presenting with osteomyelitis and fistulas with the use of carbenicillin electrophoresis (group 1: n = 20) or trypsin electrophoresis (group 2: n = 20). The treated tissues surrounding the fistulas exhibited enhanced blood circulation. In 57.1% of the observations, fistula discharge contained pathogenic flora, largely staphylococci, Gram-negative bacteria, and fungi. After the treatment, the incidence of pathogenic microflora in the patients of groups 1 and 2 was reduced to 15% and 10% respectively. It is concluded that the therapeutic modalities applied in both groups of the patients exerted the anti-inflammatory, anti-oedematous, and analgesic action suggesting improvement of hemodynamics in the region of fistula projection.

chronic osteomyelitis, carbenicillin electrophoresis, trypsin electrophoresis, immunity, local hemodynamics