Email this article Evaluation of the connective tissue dysplasia among adolescent’s population in Tyumen region
- Authors: Nagaeva M.O.1, Kolpakov V.V.1, Oslina A.N.1, Tomilova E.A.1, Bespalova T.V.2
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Affiliations:
- Tyumen state medical university
- Khanty-Mansiisk state medical academy
- Issue: Vol 29, No 5 (2022)
- Pages: 311-321
- Section: ORIGINAL STUDY ARTICLES
- URL: https://journal-vniispk.ru/1728-0869/article/view/96622
- DOI: https://doi.org/10.17816/humeco96622
- ID: 96622
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Abstract
BACKGROUND: It is crucial to organize a full-scale epidemic investigation into the rise in connective tissue dysplasia (DCT) among populations in varying climatic zones. Connective tissue dysplasia encourages the emergence and progression of several pathological conditions that harm life quality and length.
AIM: To identify the prevalence and structure of undifferentiated DCT syndrome among teenagers in different climate zones of the Tyumen region.
METHODS: An observational study in the Tyumen region, the Khanty-Mansi Autonomous Okrug-Yugra, the Yamalo-Nenets Autonomous Okrug included 578 teenagers, males, and females main groups (12 and 15 years) from secondary schools and residential schools. The evaluation of phenotypic symptoms for undifferentiated connective tissue dysplasia syndrome was according to recommendations by the Russian medical therapist’s society for diagnostics, treatment, and rehabilitation of people with DCT. The undifferentiated DCT syndrome has relevance, structure, and severity.
RESULTS: The amount of teenagers with undifferentiated DCT syndrome in the Tyumen region is 58.5%. The detection rate of undifferentiated DCT in the Tyumen region (south of the region) is 52.3%, in the Khanty-Mansi Autonomous Okrug-Yugra, it is 61.6%; in the Yamalo-Nenets Autonomous Okrug, 65.3%. Most of the registered phenotypic evidence of DCT included joint hypermobility, spinal scoliosis, hyperkyphosis of the thoracic spine, straight back syndrome, Varga index of 1.5–1.7, asthenic chest, bite anomalies, dysmorphism of the auricles, “Gothic” sky, loose and flabby skin, and myopia. A high average diagnostic coefficient, averaging 35.46±0.05 points, which surpasses the diagnostic threshold by more than two times and indicates possible complications of dysplastic changes. There are no differences in the severity of DCT manifestations according to several prognostically-significant criteria, depending on the climatic and geographical conditions within the studied area.
CONCLUSION: It is very important to take into account the high prevalence and severity of DCT among teenagers in the Tyumen region when planning programs for treatment, prophylactic, and rehabilitation measures.
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##article.viewOnOriginalSite##About the authors
Marina O. Nagaeva
Tyumen state medical university
Author for correspondence.
Email: nagaeva_m@mail.ru
ORCID iD: 0000-0003-0835-3962
SPIN-code: 6952-4984
Cand. Sci. (Med.), Associate Professor
Russian Federation, TyumenViktor V. Kolpakov
Tyumen state medical university
Email: kolpakov661@rambler.ru
ORCID iD: 0000-0001-6774-0968
SPIN-code: 6672-1697
Dr. Sci. (Med.), Professor
Russian Federation, TyumenAlexandra N. Oslina
Tyumen state medical university
Email: 0777@mail.ru
ORCID iD: 0000-0001-7846-8605
SPIN-code: 7089-1798
Russian Federation, Tyumen
Evgeniya A. Tomilova
Tyumen state medical university
Email: tomilovaea@mail.ru
ORCID iD: 0000-0003-1101-7628
SPIN-code: 4006-9259
Dr. Sci. (Med.), Associate Professor
Russian Federation, TyumenTatiana V. Bespalova
Khanty-Mansiisk state medical academy
Email: tatianadmn@mail.ru
ORCID iD: 0000-0002-7210-0946
SPIN-code: 7314-3598
Dr. Sci. (Med.), Associate Professor
Russian Federation, Khanty-MansiiskReferences
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