电邮这篇文章 Integral assessment of non-specific lipid peroxidation reactions blood in adolescent girls of the Siberian ethnos
- 作者: Darenskaya M.A.1, Rychkova L.V.1, Kolesnikov S.I.1, Semenova N.V.1, Kolesnikova L.I.1
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隶属关系:
- Scientific Centre for Family Health and Human Reproduction Problems
- 期: 卷 30, 编号 1 (2023)
- 页面: 29-39
- 栏目: ORIGINAL STUDY ARTICLES
- URL: https://journal-vniispk.ru/1728-0869/article/view/144181
- DOI: https://doi.org/10.17816/humeco105586
- ID: 144181
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BACKGROUND: Integral parameters, in particular, the oxidative stress coefficient are informative and can be used both for evaluation of pathological conditions and compensatory-adaptive reactions of the organism.
AIM: To investigate an integral coefficient the activity of nonspecific reactions of lipid peroxidation in adolescent girls of the Buryat, Evenki and Tofalar ethnic groups, as compared to the non-indigenous ethnic groups, by applying.
METHODS: Total 190 adolescent girls (Buryats, Evenki and Tofalar, and nonindigenous population (for example of Russians)) living in the Irkutsk region were the objects of research. The survey was carried out in expeditionary conditions, in the territories of compact residence of ethnic groups. To calculate the integral coefficient (oxidative stress coefficient), spectrophotometry and fluorometry methods we implemented. The individual indicators: primary, secondary, and final products of lipid peroxidation as well as antioxidant defense components were measured.
RESULTS: According to the obtained data, a lower content of diene conjugates (DC) (p <0.0001), ketodienes and conjugated trienes (KD and СT) (p=0.0003), α-tocopherol (p <0.0001) with elevated levels of TBA-active products (p=0.0074) and superoxide dismutase activity (p=0.0008) in the Buryat ethnic girls group relative to similar parameters of girls in the non-ingenious population was observed. Girls of Tofalar ethnic group had higher values of DC (p=0.0009), with reduced values of KD and CT (p=0.0044) compared to the non-indigenous population. There were no differences among girls of the Evenk ethnic group relative to Russians. An integrative analysis of the state of nonspecific lipid peroxidation reactions using the coefficient showed no significant differences between the studied groups.
CONCLUSION: The conducted study demonstrates certain changes in the “lipid peroxidation–antioxidant defence system”, in the absence of changes in the total indicator among girls representing Siberian ethnic groups and the Russian population living next to them, which can be the basis for subsequent monitoring of their health status.
作者简介
Marina Darenskaya
Scientific Centre for Family Health and Human Reproduction Problems
Email: marina_darenskaya@inbox.ru
ORCID iD: 0000-0003-3255-2013
SPIN 代码: 3327-4213
Scopus 作者 ID: 55453341400
Researcher ID: O-4490-2015
Dr. Sci. (Biol.), leader research associate
俄罗斯联邦, IrkutskLyubov Rychkova
Scientific Centre for Family Health and Human Reproduction Problems
Email: rychkova.nc@gmail.com
ORCID iD: 0000-0003-2910-0737
SPIN 代码: 1369-6575
MD, Dr. Sci. (Med.), associate member of the Russian Academy of Sciences, professor of the Russian Academy of Sciences
俄罗斯联邦, IrkutskSergey Kolesnikov
Scientific Centre for Family Health and Human Reproduction Problems
Email: iphr@sbamsr.irk.ru
ORCID iD: 0000-0003-2124-6328
SPIN 代码: 1752-6695
MD, Dr. Sci. (Med.), academician of the Russian Academy of Sciences, professor, chief research associate
俄罗斯联邦, IrkutskNatalya Semenova
Scientific Centre for Family Health and Human Reproduction Problems
Email: natkor_84@mail.ru
ORCID iD: 0000-0002-6512-1335
SPIN 代码: 6606-0160
Dr. Sci. (Biol.), leader research associate
俄罗斯联邦, IrkutskLyubov Kolesnikova
Scientific Centre for Family Health and Human Reproduction Problems
编辑信件的主要联系方式.
Email: kolesnikova20121@mail.ru
ORCID iD: 0000-0003-3354-2992
SPIN 代码: 1584-0281
MD, Dr. Sci. (Med.), academician of the Russian Academy of Sciences, professor, scientific director
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