The incidence of exacerbations of chronic generalized periodontitis in women of the reproductive age taking into consideration the cyclic changes in the levels of gonadotropic and steroid hormones

The present study included 1,329 women of the reproductive age who remained under observation during one year to elucidate the frequency and percentage of exacerbations of chronic generalized periodontitis (CGP) depending on the phase and the stage of the menstrual cycle. The incidence of exacerbations was estimated to be 75.83 per 100 women. The highest frequency of exacerbations was recorded in the late follicular (folliculin---???) and luteal phases of the cycle (40.83 and 34.24 respectively). The largest proportion of exacerbations was also found to occur in the late follicular and luteal phases (80.52% and 95.35% respectively). The results of the study pose new problems to be explored for the better understanding of the mechanisms behind exacerbations of CGP in the women of the reproductive age and for the development of optimal methods for their prevention and treatment.

chronic generalized periodontitis, menstrual cycle