The diagnostic significance of antibodies to myelin proteins in demyelinating diseases of the central nervous system

Abstract

The present article reviews the existing variants of diagnostics, ways and methods of analysis, technical means, whose working principle is based on modern physicochemical methods as applied to myelin proteins. The performed analysis testifies to a substantial amount of work done in the field of medicine and biology. Experimental study shows controversial results and, sadly enough, does not provide any comprehensive data of practical importance about reasons for demyelinating diseases and, consequently, does not allow to prognosticate the course of a disease. The development of scientific ideas about the diagnostic value of antibodies to myelin proteins in demyelinating diseases of the central nervous system from the perspective of molecular biology with the use of convergent technologies will make it possible to determine the avenue of search of solutions to the existing problem. It is a highly actual line of research nowadays, which is crucial for carrying out further study to obtain final results and apply them in clinical practice.