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Hydrolysis of aralosides from Manchurian aralia to oleanolic acid and its derivatives in subcritical water


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Abstract

A method for preparing oleanolic acid (OA) and its derivatives by the hydrolysis of aralosides from Manchurian aralia in subcritical water has been developed. It has been used for the treatment of the Saparal pharmaceutical preparation at 120–240°C in a static regime. The maximal yield of OA has been obtained at 210°C.

About the authors

O. V. Filonova

Institute of Physical and Organic Chemistry

Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090

A. V. Lekar

Institute of Physical and Organic Chemistry

Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090

S. N. Borisenko

Institute of Physical and Organic Chemistry

Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090

E. V. Vetrova

Institute of Physical and Organic Chemistry

Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090

E. V. Maksimenko

Institute of Physical and Organic Chemistry

Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090

N. I. Borisenko

Institute of Physical and Organic Chemistry

Author for correspondence.
Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090

V. I. Minkin

Institute of Physical and Organic Chemistry

Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090

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