Hydrolysis of aralosides from Manchurian aralia to oleanolic acid and its derivatives in subcritical water
- Authors: Filonova O.V.1, Lekar A.V.1, Borisenko S.N.1, Vetrova E.V.1, Maksimenko E.V.1, Borisenko N.I.1, Minkin V.I.1
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Affiliations:
- Institute of Physical and Organic Chemistry
- Issue: Vol 10, No 7 (2016)
- Pages: 1085-1091
- Section: Article
- URL: https://journal-vniispk.ru/1990-7931/article/view/198489
- DOI: https://doi.org/10.1134/S1990793116070071
- ID: 198489
Cite item
Abstract
A method for preparing oleanolic acid (OA) and its derivatives by the hydrolysis of aralosides from Manchurian aralia in subcritical water has been developed. It has been used for the treatment of the Saparal pharmaceutical preparation at 120–240°C in a static regime. The maximal yield of OA has been obtained at 210°C.
Keywords
About the authors
O. V. Filonova
Institute of Physical and Organic Chemistry
Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090
A. V. Lekar
Institute of Physical and Organic Chemistry
Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090
S. N. Borisenko
Institute of Physical and Organic Chemistry
Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090
E. V. Vetrova
Institute of Physical and Organic Chemistry
Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090
E. V. Maksimenko
Institute of Physical and Organic Chemistry
Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090
N. I. Borisenko
Institute of Physical and Organic Chemistry
Author for correspondence.
Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090
V. I. Minkin
Institute of Physical and Organic Chemistry
Email: boni@ipoc.rsu.ru
Russian Federation, Rostov-on-Don, 344090
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