Sterilization in supercritical media

D. Yu. Zalepugin; N. A. Tilkunova; I. V. Chernyshova; M. I. Vlasov

doi:10.1134/S199079311608008X

Sterilization in supercritical media

Authors: Zalepugin D.Y.¹, Tilkunova N.A.¹, Chernyshova I.V.¹, Vlasov M.I.¹
Affiliations:
1. Federal State Unitary Enterprise State Plant of Medicinal Drugs
Issue: Vol 10, No 8 (2016)
Pages: 1176-1179
Section: Article
URL: https://journal-vniispk.ru/1990-7931/article/view/198704
DOI: https://doi.org/10.1134/S199079311608008X
ID: 198704

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Abstract

This review summarizes the achievements in the field of sterilization in supercritical (SC) media in the last 10 years. In particular, new approaches to carrying out the sterilization process are described and the possible use of a wide range of SC media is shown. In addition, some data on microbial inactivation mechanism are presented and new areas of SC sterilization application are discussed.