Sterilization of a porous ultrahigh-molecular-weight polyethylene in supercritical Freons

Abstract

The possibility of sterilization of porous ultrahigh-molecular-weight polyethylene in subcritical Freons R22 and R410a in the absence of modifiers is for the first time demonstrated. The maximum sterilization effect is achieved when sterilization with Freon R410a is performed in static conditions for 30 min at 50°С and 250 bar or with Freon R22 for 60 min at 70°С and cyclically varied pressure within 100–290 bar (press–depress mode).