Some Thermodynamic Characteristics of Paracetamol Dispersing with the SEDS Method

I. Sh. Khabriev; V. F. Khairutdinov; Z. I. Zaripov; F. M. Gumerov; V. A. Petrov; N. V. Kuznetsova; R. M. Khuzakhanov

doi:10.1134/S199079311708005X

Some Thermodynamic Characteristics of Paracetamol Dispersing with the SEDS Method

Authors: Khabriev I.S.¹, Khairutdinov V.F.¹, Zaripov Z.I.¹, Gumerov F.M.¹, Petrov V.A.¹, Kuznetsova N.V.¹, Khuzakhanov R.M.¹
Affiliations:
1. Kazan National Research Technological University
Issue: Vol 11, No 8 (2017)
Pages: 1231-1245
Section: Article
URL: https://journal-vniispk.ru/1990-7931/article/view/199826
DOI: https://doi.org/10.1134/S199079311708005X
ID: 199826

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Abstract

The solubility of paracetamol in supercritical carbon dioxide and its mixtures with acetone is experientially studied. The isobaric heat capacity of paracetamol and the systems “paracetamol–CO₂” and “paracetamol–acetone–CO₂” is measured under pressures 7–29 MPa and temperatures 303–523 K. The results of paracetamol dispersing using the SEDS method (Solution Enhanced Dispersion by Supercritical Fluids) are presented.